You are being redirected because this document is part of your ASTM Compass® subscription.
    This document is part of your ASTM Compass® subscription.

    Volume 38, Issue 3 (May 1993)

    Opiate Concentrations in Human Head, Axillary, and Public Hair

    (Received 3 April 1992; accepted 3 November 1992)

    CODEN: JFSOAD

      Format Pages Price  
    PDF 6 $25   ADD TO CART

    Cite this document

    X Add email address send
    X
      .RIS For RefWorks, EndNote, ProCite, Reference Manager, Zoteo, and many others.   .DOCX For Microsoft Word



    Abstract

    The concentrations of morphine and codeine were investigated in hair from the head, axillary and public regions obtained from 12 fatal heroin cases. Hair preparation involves a decontamination procedure in dichloromethane at 37°C for 15 min, solubilization in sodium hydroxyde at 100°C for 5 min, neutralization with hydrochloric acid and centrifugation. After extraction in chloroform-isopropanol-n-heptane (50:17:33; v/v) at pH 9.2, drugs were derivatized with BSTFA + 1% TMCS and separated on a 12-m BP-5 capillary column. Quantification was done by GC/MS using selected ion monitoring. The highest morphine concentrations were found in public hair (0.80 to 41.34 ng/mg), followed by hair of the head (0.62 to 27.10 ng/mg), and axillary hair (0.40 to 24.20 ng/mg). Codeine was also detected in all samples, and the codeine-to-morphine ratios ranged from 0.069 to 0.273. The differences observed in drug concentration in the 3 types of hair are discussed in the light of the existing literature.


    Author Information:

    Kintz, P
    Forensic Scientists, Institut de Médecine Légale, Strasbourg,

    Mangin, P
    Forensic Scientists, Institut de Médecine Légale, Strasbourg,


    Stock #: JFS13452J

    ISSN: 0022-1198

    DOI: 10.1520/JFS13452J

    ASTM International
    is a member of CrossRef.

    Author
    Title Opiate Concentrations in Human Head, Axillary, and Public Hair
    Symposium , 0000-00-00
    Committee E30