ISSN: 0022-1198
CODEN: JFSCA
Page Count: 10

Substance Abuse Testing of Urine by GC/MS in Scanning Mode Evaluated by Proficiency Studies, TLC/GC, and EMIT
Goldfogel, GA
Medical Director, Whatcom Pathology Laboratory, WA

Lawson, GM
Associate Director, Toxicology Laboratory, MN

Cockerham, H
Chemistry Supervisor, Whatcom Pathology Laboratory, WA

Gibb, RP
Clinical Professor of Laboratory Medicine and Pathology, University of Washington School of Medicine, WA

Raisys, VA
Director of Toxicology and General Chemistry Sections, Harborview Medical Center, WA

(Received 14 December 1991; accepted 29 June 1992)

Abstract

Using GC/MS in scanning mode as a screening and definitive identification methodology for substance abuse testing, 4500 urine samples have been analyzed. The accuracy and sensitivity of this method was evaluated by the results of 92 proficiency sample analyses, reanalyses by TLC screening with GC confirmation of 125 samples from forensic sources and reanalysis by EMIT screening for seven groups of drugs confirmed by GC/MS of 590 samples from industrial and treatment sources. The results of these studies are presented.

Keywords:
toxicology, substance abuse testing, urine, spectroscopic analysis

Paper ID: JFS13384J
DOI: 10.1520/JFS13384J
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