Postmortem Stability of Lung Surfactant Phospholipids

    Volume 37, Issue 5 (September 1992)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Page Count: 5


    Villanueva, E
    Professor and Chairman, University of Granada,

    Lorente, JA
    Associate Professors, University of Granada, Granada,

    Lorente, M
    Associate Professors, University of Granada, Granada,

    (Received 2 December 1991; accepted 20 December 1991)

    Abstract

    The postmortem stability of the main phospholipids of lung surfactant-phosphatidyl choline (PC), phosphatydal ethanolamine (PE), phosphatydal inositol (PI), phosphatydal serine (PS) and sphyngomyelin (S) in three different deaths; one caused by fresh-water drowning, one by salt-water drowning, and one from a sodium-pentobarbital overdose has been studied. The drug overdose was considered the control because there was no surfactant involvement. The results show the stability of these kinds of lipids in the first 24 h, with a progressive decrease from 48 h on until 96 h, with a significant correlation to the time of P < 0.01 in most cases.


    Paper ID: JFS13322J

    DOI: 10.1520/JFS13322J

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    Author
    Title Postmortem Stability of Lung Surfactant Phospholipids
    Symposium , 0000-00-00
    Committee E30