Volume 37, Issue 5 (September 1992)

    Robotic Method for the Analysis of Morphine and Codeine in Urine

    (Received 18 November 1991; accepted 30 December 1991)

    CODEN: JFSOAD

      Format Pages Price  
    PDF 12 $25   ADD TO CART


    Abstract

    A totally automated procedure has been developed for the detection and quantitation of morphine and codeine in urine case samples. The samples were initially screened for these drugs by a SyvaR EMIT Toxicology System (ETS™). A Zymate™ laboratory robotic system confirms positive samples from SyvaR ETS by performing the hydrolysis, extraction, and derivatization of morphine and codeine. The derivatized morphine and codeine were detected using gas chromatography/mass spectrometry (GC/MS). Enzymatic hydrolysis conditions were experimentally optimized during method development. The automation of these procedures has proven to be reliable and efficient.


    Author Information:

    Vidal, DL
    Senior Criminalist, Los Angeles County Sheriff's Department, Scientific Services Bureau, Toxicology Section, Los Angeles, CA

    Ting, EJ
    Senior Criminalist, Los Angeles County Sheriff's Department, Scientific Services Bureau, Toxicology Section, Los Angeles, CA

    Taylor, RW
    Senior Criminalist, Los Angeles County Sheriff's Department, Scientific Services Bureau, Toxicology Section, Los Angeles, CA

    Le, SD
    Supervising Criminalist, Los Angeles County Sheriff's Department, Scientific Services Bureau, Toxicology Section,

    Perez, SL
    Criminalistics Laboratory Technician, Los Angeles County Sheriff's Department, Scientific Services Bureau, Toxicology Section,


    Stock #: JFS13316J

    ISSN: 0022-1198

    DOI: 10.1520/JFS13316J

    ASTM International
    is a member of CrossRef.

    Author
    Title Robotic Method for the Analysis of Morphine and Codeine in Urine
    Symposium , 0000-00-00
    Committee E30