Journal Published Online: 01 November 1991
Volume 36, Issue 6

Isolation, Identification, and Origin of Three Previously Unknown Congeners in Illicit Cocaine

CODEN: JFSCAS

Abstract

Three previously unknown, overlooked, or perhaps wrongly identified impurities in illicit cocaine seized in the Netherlands Antilles are traced by various combinations of chromatographic and extraction methods. Once isolated using high-performance liquid chromatography, the compounds are identified as norcocaine, N-benzoylnorecgnonine methyl ester, and N-formyl norcocaine. Their presence in the illicit cocaine samples is explained as a result of the permanganate bleaching procedure that is nowadays routinely performed as part of the illegal production protocol.

Author Information

Ensing, JG
University Centre for Pharmacy, University of Groningen, Groningen, The Netherlands
Hummelen, JC
Laboratory for Organic Chemistry, University of Groningen, The Netherlands
Pages: 22
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Stock #: JFS13191J
ISSN: 0022-1198
DOI: 10.1520/JFS13191J