Journal Published Online: 01 November 1991
Volume 36, Issue 6

A Rapid Method for the Determination of Cocaine in Brain Tissue

CODEN: JFSCAS

Abstract

A rapid procedure is described for the extraction and analysis of brain samples for cocaine and benzoylecgonine. Human brain tissue was sectioned at autopsy, and samples were subjected to a lipase digestion, subsequent to solid-phase extraction. The distribution of cocaine and benzoylecgonine throughout different regions of the brain was determined by high-performance liquid chromatography.

Author Information

Browne, SP
University of Illinois at Chicago, Chicago, IL
Moore, CM
University of Illinois at Chicago, Chicago, IL
Scheurer, J
University of Illinois at Chicago, Chicago, IL
Tebbett, IR
University of Illinois at Chicago, Chicago, IL
Logan, BK
Washington State Toxicology Laboratory, Department of Laboratory Medicine, University of Washington, Seattle, WA
Pages: 4
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Stock #: JFS13190J
ISSN: 0022-1198
DOI: 10.1520/JFS13190J