Volume 36, Issue 6 (November 1991)

    A Rapid Method for the Determination of Cocaine in Brain Tissue

    (Received 14 February 1991; accepted 19 April 1991)

    CODEN: JFSOAD

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    Abstract

    A rapid procedure is described for the extraction and analysis of brain samples for cocaine and benzoylecgonine. Human brain tissue was sectioned at autopsy, and samples were subjected to a lipase digestion, subsequent to solid-phase extraction. The distribution of cocaine and benzoylecgonine throughout different regions of the brain was determined by high-performance liquid chromatography.


    Author Information:

    Logan, BK
    Chief toxicologist, Washington State Toxicology Laboratory, Department of Laboratory Medicine, University of Washington, Seattle, WA

    Moore, CM
    Graduate student, research assistant, graduate student, and assistant professor, University of Illinois at Chicago, Chicago, IL

    Tebbett, IR
    Graduate student, research assistant, graduate student, and assistant professor, University of Illinois at Chicago, Chicago, IL

    Scheurer, J
    Graduate student, research assistant, graduate student, and assistant professor, University of Illinois at Chicago, Chicago, IL

    Browne, SP
    Graduate student, research assistant, graduate student, and assistant professor, University of Illinois at Chicago, Chicago, IL


    Stock #: JFS13190J

    ISSN: 0022-1198

    DOI: 10.1520/JFS13190J

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    Author
    Title A Rapid Method for the Determination of Cocaine in Brain Tissue
    Symposium , 0000-00-00
    Committee E30