Journal Published Online: 01 September 1991
Volume 36, Issue 5

A Chromatographic Impurity Signature Profile Analysis for Cocaine Using Capillary Gas Chromatography

CODEN: JFSCAS

Abstract

The signature patterns of cocaine samples were examined by capillary gas chromatography using 14 impurities commonly found in illicit cocaine samples. The procedure is based on acidic, basic, and neutral impurities introduced from the coca plant and from the processing of cocaine in clandestine laboratories. Impurities containing either alcoholic, N-nor, or carboxylic acid functional groups were analyzed as their silyl derivatives. The reported procedure provides a simple one-step assay for obtaining chromatographic impurity signature profile analyses (CISPA) of illicit cocaine samples using flame ionization detection (FID).

Author Information

Casale, JF
Drug Chemistry Laboratory, State Bureau of Investigation, Raleigh, NC
Waggoner, RW
Drug Chemistry Laboratory, State Bureau of Investigation, Raleigh, NC
Pages: 19
Price: $25.00
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Stock #: JFS13154J
ISSN: 0022-1198
DOI: 10.1520/JFS13154J