Journal Published Online: 01 November 1990
Volume 35, Issue 6

Capillary Gas-Liquid Chromatography Separation of Phenethylamines in Amphetamine-Positive Urine Samples

CODEN: JFSCAS

Abstract

Good gas chromatography (GC) separation of molecules is essential for clean gas chromatography/mass spectrometry (GC/MS) confirmation of compounds. The trifluoro derivatives of ephedrine (E) and methamphetamine (MA) coelute on dimethyl silicone capillary columns, such as DB-1, which are most commonly used by chromatographers. Methods are described to separate E and MA to aid GC/MS confirmations of methamphetamine, ephedrine, or both E and MA together, whichever may be present in Enzyme Immunoassay (EIA)-analyzed amphetamine-positive urine samples. The use of the heptafluoro derivatives of E and MA on a DB-1 column, or the trifluoro derivatives of E and MA on a DB-17 column, is suggested for good gas chromatographic separation.

Author Information

DePace, A
New York State Psychiatric Institute, New York, NY
Verebey, K
State University of New York Health Science Center, Brooklyn, NY
ElSohly, M
ElSohly Laboratories, Inc., Oxford, MS
Pages: 5
Price: $25.00
Related
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Details
Stock #: JFS12979J
ISSN: 0022-1198
DOI: 10.1520/JFS12979J