Volume 35, Issue 6 (November 1990)

    Use of Deoxyribonucleic Acid (DNA) Fingerprints for Identity Determination: Comparison with Traditional Paternity Testing Methods—Part II

    (Received 11 July 1988; accepted 29 December 1989)

    CODEN: JFSOAD

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    Abstract

    Six red blood cell (RBC) antigen systems, coupled with human lymphocyte antigen (HLA) phenotyping, were used to establish paternity on 28 mother/child/allegedfather trios. Samples were subsequently examined using the deoxyribonucleic acid (DNA) fingerprinting test with the multilocus Jeffreys DNA probes 33.6 and 33.15. In 27 of 28 paternity cases, the DNA fingerprinting test results supported and enhanced the results of RBC and HLA typing by resolving disputed paternity cases conclusively. One discrepancy between conventional serological methods and DNA analysis is discussed.


    Author Information:

    Garner, DD
    Laboratory supervisor, manager of the Research and Development Laboratory, and director of laboratories, Cellmark Diagnostics, Germantown, MD

    Green, DJ
    President, BMA Labs, Woburn, MA

    Herrin, GL
    DNA Unit supervisor, Georgia Bureau of Investigation, Division of Forensic Sciences, Decatur, GA

    Gottschall, JL
    Associate medical director, Blood Center of Southeastern Wisconsin, Milwaukee, WI

    Markowicz, KR
    Technical specialist, Finnegan, Henderson, Farabow, Garrett, and Dunner, Washington, DC

    Tonelli, LA
    Laboratory supervisor, manager of the Research and Development Laboratory, and director of laboratories, Cellmark Diagnostics, Germantown, MD

    Anderson, MB
    Laboratory manager, Cellmark Diagnostics, Germantown, MD

    Cotton, RW
    Laboratory supervisor, manager of the Research and Development Laboratory, and director of laboratories, Cellmark Diagnostics, Germantown, MD


    Stock #: JFS12960J

    ISSN: 0022-1198

    DOI: 10.1520/JFS12960J

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    Author
    Title Use of Deoxyribonucleic Acid (DNA) Fingerprints for Identity Determination: Comparison with Traditional Paternity Testing Methods—Part II
    Symposium , 0000-00-00
    Committee E30