ISSN: 0022-1198
CODEN: JFSCA
Page Count: 5

Restriction Fragment Length Polymorphism DNA Analysis by the FBI Laboratory Protocol Using a Simple, Convenient Hardware System
Latorra, D
Director, Laboratory of Molecular Biology, director of research, and manager, Technical Services, BIOS Corp., CT

Lee, HC
Chief criminalist and director, Connecticut State Police Forensic Science Laboratory, CT

Berka, KM
Research associate, and professor and director, Forensic Sciences Program and Laboratories, University of New Haven, CT

Lewis, ME
Director, Laboratory of Molecular Biology, director of research, and manager, Technical Services, BIOS Corp., CT

Gaensslen, RE
Research associate, and professor and director, Forensic Sciences Program and Laboratories, University of New Haven, CT

Kouri, RE
Director, Laboratory of Molecular Biology, director of research, and manager, Technical Services, BIOS Corp., CT

(Received 1 November 1989; accepted 20 November 1989)

Abstract

Restriction fragment length polymorphism analysis of human deoxyribonucleic acid (DNA) using two probes, pYNH24 and CMM101, was performed on the BIOS Timeframe™ system following the Federal Bureau of Investigation (FBI) Laboratory protocol and some variations of it. Comparable results were obtained by the different methods used.

Keywords:
forensic science, pathology and biology, deoxyribonucleic acid (DNA), restriction fragment length polymorphism (RFLP), DNA analysis, forensic serology, variable-number-of-tandem-repeats polymorphism

Paper ID: JFS12942J
DOI: 10.1520/JFS12942J
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