Solid-Phase Extraction, Identification, and Quantitation of 11-Nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid

    Volume 35, Issue 4 (July 1990)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Page Count: 5


    Nakamura, GR
    Chief chemist and forensic chemists, U.S. Army Criminal Investigation Laboratory—Pacific, APO San Francisco, CA

    Meeks, RD
    Chief chemist and forensic chemists, U.S. Army Criminal Investigation Laboratory—Pacific, APO San Francisco, CA

    Stall, WJ
    Chief chemist and forensic chemists, U.S. Army Criminal Investigation Laboratory—Pacific, APO San Francisco, CA

    (Received 12 June 1989; accepted 11 July 1989)

    Abstract

    A procedure has been developed to extract and recover minute amounts of delta-9-carboxytetrahydrocannabinol (THC-COOH) from urine. A new non-isotopic internal standard is introduced to permit a chromatographic assay of the metabolite. The method affords a 91% recovery of 20 ng/mL of the THC-COOH acid from spiked urine with the assurance of a 3.8% coefficient of variation.


    Paper ID: JFS12891J

    DOI: 10.1520/JFS12891J

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    Title Solid-Phase Extraction, Identification, and Quantitation of 11-Nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid
    Symposium , 0000-00-00
    Committee E30