Volume 35, Issue 3 (May 1990)

    Undiagnosed, Untreated Acute Lymphoblastic Leukemia Presenting as Suspected Child Abuse

    (Received 22 May 1989; accepted 16 June 1989)

    CODEN: JFSOAD

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    Abstract

    Natural disease being mistaken for child abuse is rare. A two-year-old child was found unresponsive at home and transported to a local hospital, where she expired in the emergency room. Several cutaneous contusions were observed. Prior to the autopsy it was learned that an anonymous report of “child abuse” had been previously filed concerning this child. At autopsy there were multiple metasynchronous cutaneous contusions, but no radiologic or gross evidence of other injuries. A pericardial effusion, massive hepatosplenomegaly and generalized lymphadenopathy were apparent. The bone marrow, liver, spleen, lymph nodes, kidneys, pancreas, heart, stomach, and dura mater showed a monotonous lymphocytic infiltrate. Immunocytochemical studies confirmed the diagnosis of acute lymphoblastic leukemia of childhood. This case reaffirms the need for an objective examination of all cases by a forensic pathologist.


    Author Information:

    Sandusky, GE
    Senior pathologist, Lilly Research Laboratories, Greenfield, IN

    McClain, JL
    Fellow in forensic pathology and associate professor of pathology, Indiana University School of Medicine, Indianapolis, IN

    Clark, MA
    Fellow in forensic pathology and associate professor of pathology, Indiana University School of Medicine, Indianapolis, IN


    Stock #: JFS12881J

    ISSN: 0022-1198

    DOI: 10.1520/JFS12881J

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    Author
    Title Undiagnosed, Untreated Acute Lymphoblastic Leukemia Presenting as Suspected Child Abuse
    Symposium , 0000-00-00
    Committee E30