Journal Published Online: 01 January 1990
Volume 35, Issue 1

Isotopic Analog as the Internal Standard for Quantitative Determination: Evaluation of Mass Spectra of Commonly Abused Drugs and Their Deuterated Analogs

CODEN: JFSCAS

Abstract

Mass spectra of several commonly abused drugs and their deuterated analogs are compared and evaluated with emphasis on the selection of suitable ions for selective ion monitoring when the isotopic analogs are used as the internal standards in a quantitative determination process. Ions selected for this purpose should be of relative high mass with significant intensities, retain at least three labeling isotopes, and be free of interference from the corresponding compound.

Author Information

Ho, YS
University of Alabama at Birmingham, Birmingham, AL
Liu, RH
University of Alabama at Birmingham, Birmingham, AL
Nichols, AW
Radian Corporation, Austin, TX
Kumar, SD
Radian Corporation, Austin, TX
Pages: 10
Price: $25.00
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Stock #: JFS12809J
ISSN: 0022-1198
DOI: 10.1520/JFS12809J