Volume 35, Issue 1 (January 1990)

    Opiate Analysis in Cadaveric Blowfly Larvae as an Indicator of Narcotic Intoxication

    (Received 19 December 1988; accepted 9 February 1989)

    CODEN: JFSOAD

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    Abstract

    Specimens of liver were collected from 40 cases in which the cause of death had been determined to be opiate intoxication. Rearings of Calliphora vicina larvae were then promoted on the decomposing liver. A control group of 10 decomposed liver specimens from non-opiate deaths was treated similarly. Analysis of larvae and liver for opiates (morphine) was conducted by radioimmunoassay. Good qualitative and quantitative correlation was observed in both the positive and negative groups. Regression analysis comparing the concentrations of opiates found in the larvae with those found in the liver in the positive group resulted in a correlation of r = 0.790.


    Author Information:

    Dico, CL
    Assistant toxicologist, toxicologist, and chief medical examiner, Office of the Chief Medical Examiner, Baltimore, MD

    Introna, F
    Fellow in forensic pathology, University of Maryland, Baltimore, MD

    Smialek, JE
    Assistant toxicologist, toxicologist, and chief medical examiner, Office of the Chief Medical Examiner, Baltimore, MD

    Caplan, YH
    Assistant toxicologist, toxicologist, and chief medical examiner, Office of the Chief Medical Examiner, Baltimore, MD


    Stock #: JFS12808J

    ISSN: 0022-1198

    DOI: 10.1520/JFS12808J

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    Title Opiate Analysis in Cadaveric Blowfly Larvae as an Indicator of Narcotic Intoxication
    Symposium , 0000-00-00
    Committee E30