Journal Published Online: 01 May 1989
Volume 34, Issue 3

Development and Application of Immunoassay for Paraquat: Radioimmunoassay

CODEN: JFSCAS

Abstract

A sensitive radioimmunoassay for paraquat is reported. Anti-paraquat antisera were produced by repeated immunization in rabbits with 1-methyl,1′-hexanoic acid-4,4′-bipyridinium (MHBP) coupled to bovine serum albumin (BSA). Less than 0.5 ng of paraquat dichloride was detectable by this assay system. These antisera were strongly cross-reactive with the bipyridyl ring and methyl group in either the 1- or 1′-position of paraquat. The determination of paraquat in tissues of paraquat-poisoned cadavers was also carried out.

Author Information

Nagao, M
Hokkaido University School of Medicine, Sapporo, Japan
Takatori, T
Hokkaido University School of Medicine, Sapporo, Japan
Terazawa, K
Hokkaido University School of Medicine, Sapporo, Japan
Wu, B
Hokkaido University School of Medicine, Sapporo, Japan
Wakasugi, C
Wakayama Medical College, Wakayama, Japan
Masui, M
Wakayama Medical College, Wakayama, Japan
Ikeda, H
Wakayama Medical College, Wakayama, Japan
Pages: 6
Price: $25.00
Related
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Details
Stock #: JFS12675J
ISSN: 0022-1198
DOI: 10.1520/JFS12675J