ISSN: 0022-1198
Page Count: 4

Fatal Intoxication by Remoxipride
Penttilä, A
Resident in forensic medicine, chief chemist, chemist, and associate professor of forensic toxicology, University of Helsinki,

Vuori, E
Resident in forensic medicine, chief chemist, chemist, and associate professor of forensic toxicology, University of Helsinki,

Lukkari, I
Resident in forensic medicine, chief chemist, chemist, and associate professor of forensic toxicology, University of Helsinki,

Segerberg-Konttinen, M
Resident in forensic medicine, chief chemist, chemist, and associate professor of forensic toxicology, University of Helsinki,

(Received 7 January 1988; accepted 21 June 1988)

Abstract

The case history and toxicologic findings of a 23-year-old woman who committed suicide with Remoxipride are described. Remoxipride® is a recently developed neuroleptic drug of the benzamide type. Remoxipride was detected in the liver, stomach content, blood, and urine. The concentration of Remoxipride in the blood was 230 mg/L. The recommended therapeutic level for Remoxipride should not exceed 7 to 8 mg/L. The victim had no blood alcohol, but an ethanol concentration of 0.048 g/100 L was detected in the urine. The mechanism of death from Remoxipride intoxication is not known. In clinical studies, sinus bradycardia and infrequent supraventricular and ventricular ectopic beats have been noted.

Keywords:
pathology and biology, toxicology, Remoxipride, suicide, medicolegal autopsy, intoxication

Paper ID: JFS12666J
DOI: 10.1520/JFS12666J
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