Forensic chemist, Drug Enforcement Administration, Southeast Laboratory, Miami, FL
(Received 8 August 1987; accepted 20 October 1987)
Nitromethaqualone [2-methyl-3(2′-methoxy-4′-nitrophenyl)-4(3H)-quinazolinone] and its three positional isomers formed by moving the nitro group on the phenyl ring containing the 2′-methoxyl group have been synthesized and characterized. Mass spectra, infrared spectra, nuclear magnetic resonance spectra, and the gas-liquid chromatographic behavior of these compounds are presented. It is shown that infrared spectroscopy, nuclear magnetic resonance spectroscopy, and electron impact mass spectroscopy combined with gas-liquid chromatography are capable of differentiating nitromethaqualone from any of the studied isomers, methaqualone, and mecloqualone.
Paper ID: JFS12528J