ISSN: 0022-1198
CODEN: JFSCA
Page Count: 7

Fourier Transform-Infrared (FT-IR) Characterization of the Ethyl Acetate Complex of O⁶-Acetylmorphine
Neville, GA
Technologist and head of spectroscopy section, Drug Identification Division, Bureau of Drug Research, Health Protection Branch, Health and Welfare Canada, Ontario

Beckstead, HD
Technologist and head of spectroscopy section, Drug Identification Division, Bureau of Drug Research, Health Protection Branch, Health and Welfare Canada, Ontario

(Received 21 February 1987; accepted 4 May 1987)

Abstract

The solid-state infrared spectral features of the (1:1) O⁶-acetylmorphine-ethyl acetate complex are compared to those of its host, O⁶-acetylmorphine base, and to its very similar analog, O³,O⁶-diacetylmorphine (heroin). The formation of a stable complex appears to be unique to O⁶-acetylmorphine for neither morphine nor its closely related derivatives, codeine, thebaine, heroin, or O³-acetylmorphine form isolable adducts during ethyl acetate extraction. Factors affecting formation of this complex during workup and extraction of forensic science exhibits are discussed.

Keywords:
toxicology, extraction, ethyl acetate complex, heroin, spectroscopic analysis

Paper ID: JFS12454J
DOI: 10.1520/JFS12454J
ASTM International is a member of CrossRef.