ISSN: 0022-1198
CODEN: JFSCA
Page Count: 6

A Carpipramine Related Fatality
Fraser, AD
Head, Toxicology Laboratory, Victoria General Hospital, Nova Scotia

Isner, AF
Chemist, Toxicology Laboratory, Victoria General Hospital, Nova Scotia

(Received 5 July 1986; accepted 26 August 1986)

Abstract

A fatality following ingestion of the tricyclic antidepressant carpipramine (Prazinil®) and ethyl alcohol is described. Carpipramine was quantitated by high performance liquid chromatography. The concentration of carpipramine was 2.0 mg/L in blood and 0.44 mg/L in urine. Ethyl alcohol was measured by headspace gas chromatography and found to be 105 mg/dL in blood and 55 mg/dL in the urine. Quantitative analysis of stomach contents was positive for carpipramine by thin-layer chromatography. To our knowledge, this is the first reported fatality involving carpipramine.

Keywords:
pathology and biology, carpipramine, death, chromatographic analysis

Paper ID: JFS12423J
DOI: 10.1520/JFS12423J
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