Head, Toxicology Laboratory, Victoria General Hospital, Halifax, Nova Scotia
Chemist, Toxicology Laboratory, Victoria General Hospital, Halifax, Nova Scotia
(Received 5 July 1986; accepted 26 August 1986)
A fatality following ingestion of the tricyclic antidepressant carpipramine (Prazinil®) and ethyl alcohol is described. Carpipramine was quantitated by high performance liquid chromatography. The concentration of carpipramine was 2.0 mg/L in blood and 0.44 mg/L in urine. Ethyl alcohol was measured by headspace gas chromatography and found to be 105 mg/dL in blood and 55 mg/dL in the urine. Quantitative analysis of stomach contents was positive for carpipramine by thin-layer chromatography. To our knowledge, this is the first reported fatality involving carpipramine.
Paper ID: JFS12423J