Methamphetamine from Ephedrine: I. Chloroephedrines and Aziridines

    Volume 32, Issue 4 (July 1987)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Page Count: 10


    Allen, AC
    Forensic chemist, Drug Enforcement Administration, Western Field Laboratory, San Francisco, CA

    Kiser, WO
    Forensic chemist, Drug Enforcement Administration, Southeast Field Laboratory, Miami, FL

    (Received 29 May 1986; accepted 9 August 1986)

    Abstract

    Illicit methamphetamine clandestinely synthesized from ephedrine via reduction of chloroephedrine is discussed. The stereochemistry, mechanism, synthetic impurities, and analysis of clandestine methamphetamine samples is addressed. Stereochemical relation of (+)methamphetamine to its initial precursor (−)ephedrine or (+)pseudoephedrine is achieved by detection of (+)chloropseudoephedrine or cis-1,2-dimethyl-3-phenylaziridine, in the case of the first, and (-)chloroephedrine or trans-1,2-dimethyl-3-phenylaziridine in the case of the latter.


    Paper ID: JFS12406J

    DOI: 10.1520/JFS12406J

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    Title Methamphetamine from Ephedrine: I. Chloroephedrines and Aziridines
    Symposium , 0000-00-00
    Committee E30