The Separation of Lysergide (LSD) from Related Ergot Alkaloids and Its Identification in Forensic Science Casework Samples

    Volume 32, Issue 4 (July 1987)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Page Count: 8


    David Osselton, M
    Higher scientific officer, senior scientific officer, and principal scientific officer, Central Research Establishment, Home Office Forensic Science Service, Aldermaston, Reading Berks,

    Japp, M
    Higher scientific officer, senior scientific officer, and principal scientific officer, Central Research Establishment, Home Office Forensic Science Service, Aldermaston, Reading Berks,

    Gill, R
    Higher scientific officer, senior scientific officer, and principal scientific officer, Central Research Establishment, Home Office Forensic Science Service, Aldermaston, Reading Berks,

    (Received 31 July 1986; accepted 10 October 1986)

    Abstract

    The separation of lysergide (LSD) from related ergot alkaloids, and its isomer lysergic acid methylpropylamide (LAMPA), has been investigated using the techniques of capillary gas chromatography and high performance liquid chromatography (HPLC). Capillary gas chromatography using fused silica nonpolar bonded phase columns gave good discrimination, and retention indices for several ergot alkaloids have been measured. The applicability of this technique to the analysis of illicit LSD preparations has been demonstrated by preparing extracts from LSD microdot tablets and card and paper squares. The HPLC systems examined in the present study were unable to achieve baseline resolution of LSD and LAMPA.


    Paper ID: JFS12404J

    DOI: 10.1520/JFS12404J

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    Title The Separation of Lysergide (LSD) from Related Ergot Alkaloids and Its Identification in Forensic Science Casework Samples
    Symposium , 0000-00-00
    Committee E30