School of Pharmacy, Auburn University, Auburn, AL
Taylor Noggle, F
Criminalist, Alabama Department of Forensic Sciences, Auburn, AL
(Received 29 June 1985; accepted 10 July 1985)
The high-performance liquid chromatographic resolution of the enantiomers of amphetamine, methamphetamine, ephedrine, and pseudoephedrine is described. The sugar isothiocyanate, 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate (GITC), is used as a chiral derivatizing agent, with chromatographic separations of the diastereomers formed with each amine made using a standard achiral C18 stationary phase.
Paper ID: JFS12307J