Profiles of Δ9-Tetrahydrocannabinol Metabolites in Urine of Marijuana Users: Preliminary Observations by High Performance Liquid Chromatography-Radioimmunoassay

    Volume 31, Issue 2 (April 1986)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Page Count: 12


    Peat, MA
    Codirector, Chemical Toxicology, Institute, Foster City, CA

    Alburges, ME
    Graduate student, University of Utah, Salt Lake City, UT

    (Received 20 April 1985; accepted 10 August 1985)

    Abstract

    Metabolic profiles of 11-nor-9-carboxylic acid-Δ9-tetrahydrocannabinol (COOH-THC) and other THC metabolites were determined in an infrequent and a frequent marijuana user by high performance liquid chromatography-radioimmunoassay (HPLC-RIA). In the infrequent user, no unconjugated COOH-THC was detected in urine samples for the first 8 h following smoking, whereas this metabolite was detected in the urine samples from a frequent user. A metabolite was also detected in the frequent user, which was not present in the urine sample from the infrequent user.


    Paper ID: JFS12302J

    DOI: 10.1520/JFS12302J

    ASTM International
    is a member of CrossRef.

    Author
    Title Profiles of Δ9-Tetrahydrocannabinol Metabolites in Urine of Marijuana Users: Preliminary Observations by High Performance Liquid Chromatography-Radioimmunoassay
    Symposium , 0000-00-00
    Committee E30