Report of a Metoprolol-Associated Death

    Volume 27, Issue 3 (July 1982)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 July 1982

    Page Count: 3


    Ellenberger, HA
    Toxicologist, Department of Pathology, Victoria General Hospital, Halifax, Nova Scotia

    Holzbecher, M
    Technologist, Department of Pathology, Victoria General Hospital, Halifax, Nova Scotia

    Perry, RA
    Chief medical examiner for Halifax County, Department of Attorney General, Halifax, Nova Scotia

    (Received 16 November 1981; accepted 14 December 1981)

    Abstract

    The case history and toxicological findings relative to a death associated with metoprolol overdose are described. Metoprolol concentrations in blood, vitreous humor, and bile were 5.6, 4.2, and 28 mg/dL, respectively; the maximum liver concentration was 260μg/g. Concentrations in the liver obtained by direct extraction, Ketodase (β-glucuronidase) digestion, and hydrochloric acid digestion are compared.


    Paper ID: JFS12180J

    DOI: 10.1520/JFS12180J

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    Title Report of a Metoprolol-Associated Death
    Symposium , 0000-00-00
    Committee E30