Published Online: 1 July 1982
Page Count: 3
Toxicologist, Department of Pathology, Victoria General Hospital, Halifax, Nova Scotia
Technologist, Department of Pathology, Victoria General Hospital, Halifax, Nova Scotia
Chief medical examiner for Halifax County, Department of Attorney General, Halifax, Nova Scotia
(Received 16 November 1981; accepted 14 December 1981)
The case history and toxicological findings relative to a death associated with metoprolol overdose are described. Metoprolol concentrations in blood, vitreous humor, and bile were 5.6, 4.2, and 28 mg/dL, respectively; the maximum liver concentration was 260μg/g. Concentrations in the liver obtained by direct extraction, Ketodase (β-glucuronidase) digestion, and hydrochloric acid digestion are compared.
Paper ID: JFS12180J