ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 July 1982
Page Count: 3

Report of a Metoprolol-Associated Death
Ellenberger, HA
Toxicologist, Department of Pathology, Victoria General Hospital, Nova Scotia

Holzbecher, M
Technologist, Department of Pathology, Victoria General Hospital, Nova Scotia

Perry, RA
Chief medical examiner for Halifax County, Department of Attorney General, Nova Scotia

(Received 16 November 1981; accepted 14 December 1981)

Abstract

The case history and toxicological findings relative to a death associated with metoprolol overdose are described. Metoprolol concentrations in blood, vitreous humor, and bile were 5.6, 4.2, and 28 mg/dL, respectively; the maximum liver concentration was 260μg/g. Concentrations in the liver obtained by direct extraction, Ketodase (β-glucuronidase) digestion, and hydrochloric acid digestion are compared.

Keywords:
toxicology, metoprolol, death

Paper ID: JFS12180J
DOI: 10.1520/JFS12180J
ASTM International is a member of CrossRef.