Identification of the Major Impurities in the Illicit Manufacture of Tryptamines and Related Compounds

    Volume 27, Issue 3 (July 1982)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 July 1982

    Page Count: 14


    Holtham, AL
    Drugs and Toxicology Section, Metropolitan Police Forensic Science Laboratory, London,

    Cowie, JS
    Drugs and Toxicology Section, Metropolitan Police Forensic Science Laboratory, London,

    Jones, LV
    Mass Spectrometry Section, North Western Forensic Science Laboratory, Chorley, Lancashire

    (Received 17 October 1981; accepted 2 December 1981)

    Abstract

    N-[1-hydroxy-2-(3-indolyl)ethyl] pyrrolidine was detected as an impurity in N-[2-(3-indolyl)ethyl] pyrrolidine (tetramethylene tryptamine). 1-(N,N-diethlyamino)-2-(3-indo-lyl)ethan-1-ol together with 2-(3-indolyl)ethan-1-ol were detected as impurities 1-(N,N-diethyl-amino)-2-(3-indolyl)-ethane (N,N-diethyl tryptamine). These impurities indicate that the synthetic route was that of Misztal and such information is important.


    Paper ID: JFS12165J

    DOI: 10.1520/JFS12165J

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    Title Identification of the Major Impurities in the Illicit Manufacture of Tryptamines and Related Compounds
    Symposium , 0000-00-00
    Committee E30