ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 July 1982
Page Count: 14

Identification of the Major Impurities in the Illicit Manufacture of Tryptamines and Related Compounds
Holtham, AL
Drugs and Toxicology Section, Metropolitan Police Forensic Science Laboratory,

Cowie, JS
Drugs and Toxicology Section, Metropolitan Police Forensic Science Laboratory,

Jones, LV
Mass Spectrometry Section, North Western Forensic Science Laboratory, Lancashire

(Received 17 October 1981; accepted 2 December 1981)

Abstract

N-[1-hydroxy-2-(3-indolyl)ethyl] pyrrolidine was detected as an impurity in N-[2-(3-indolyl)ethyl] pyrrolidine (tetramethylene tryptamine). 1-(N,N-diethlyamino)-2-(3-indo-lyl)ethan-1-ol together with 2-(3-indolyl)ethan-1-ol were detected as impurities 1-(N,N-diethyl-amino)-2-(3-indolyl)-ethane (N,N-diethyl tryptamine). These impurities indicate that the synthetic route was that of Misztal and such information is important.

Keywords:
toxicology, chemical analysis, tryptamine

Paper ID: JFS12165J
DOI: 10.1520/JFS12165J
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