Distribution of Gene Frequencies and Discrimination Probabilities for 22 Human Blood Genetic Systems in Four Racial Groups

    Volume 25, Issue 2 (April 1980)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 April 1980

    Page Count: 17


    Myhre, BA
    Professor of pathology, University of California Los Angeles School of Medicine, Harbor UCLA Medical Center Campus, Harbor General Hospital, Torrance, Calif.

    Grunbaum, BW
    Research biochemist, University of California, Berkeley,

    Pace, N
    Research biochemist, University of California, Berkeley,

    Selvin, S
    Research biochemist, University of California, Berkeley,

    (Received 3 August 1979; accepted 7 December 1979)

    Abstract

    Gene frequencies were computed in four racial categories from 5956 blood donors from California, Hawaii, Mexico City, and Texas. Calculations were based on the phenotypic distribution of 22 blood genetic systems including 7 blood groups and 15 genetically controlled polymorphic proteins and enzymes. Matching probabilities for 20 systems were approximately 1 in 100 000 Asians, 1 in 200 000 blacks, 1 in 330 000 Mexicans, and 1 in 1 000 000 whites. The complementary discrimination probability, which measures the likelihood that two random individuals do not match, was, for practical purposes, unity. The combined new technology for blood grouping and electrophoresis using cellulose acetate membranes provides a powerful individualizing and discriminating tool for forensic science investigation.


    Paper ID: JFS12150J

    DOI: 10.1520/JFS12150J

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    Title Distribution of Gene Frequencies and Discrimination Probabilities for 22 Human Blood Genetic Systems in Four Racial Groups
    Symposium , 0000-00-00
    Committee E30