Persistence of Morphine in Blood in Association with Hepatic Necrosis and Renal Tubular Necrosis

    Volume 25, Issue 2 (April 1980)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 April 1980

    Page Count: 3


    Wiseley, DV
    Chief, Department of Chief Medical Examiner-Coroner, Los Angeles, Calif

    Nakamura, GR
    Chief, Department of Chief Medical Examiner-Coroner, Los Angeles, Calif

    (Received 30 May 1979; accepted 19 October 1979)

    Abstract

    A case is reported in which a 26-year-old male survived in a hospital for 38 h after an intravenous heroin injection. Postmortem analysis showed 0.2 mg/100 ml morphine in the blood and 0.05 mg/100 g morphine in the liver. The persistence of morphine in the blood was attributed to the inability of damaged liver cells to take up the morphine and of the hypoxic kidney to excrete the compound.


    Paper ID: JFS12137J

    DOI: 10.1520/JFS12137J

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    Title Persistence of Morphine in Blood in Association with Hepatic Necrosis and Renal Tubular Necrosis
    Symposium , 0000-00-00
    Committee E30