ISSN: 0022-1198
CODEN: JFSCA
Page Count: 4

Chorionic Villus Sampling Prior to Pregnancy Termination, a Tool for Forensic Paternity Testing
Marbach, A
Head, Forensic Biology Laboratory, Division of Identification and Forensic Science, Israel Police National Headquarters,

Reshef, A
Forensic biologist, Forensic Biology Laboratory, Division of Identification and Forensic Science, Israel Police National Headquarters,

Shmueli, E
Tissue culture biologist, Hadassah University Hospital,

Shpitzen, M
Forensic biologist, Forensic Biology Laboratory, Division of Identification and Forensic Science, Israel Police National Headquarters,

Gallili, N
Forensic biologist, Forensic Biology Laboratory, Division of Identification and Forensic Science, Israel Police National Headquarters,

Brauner, P
Forensic biologist, Forensic Biology Laboratory, Division of Identification and Forensic Science, Israel Police National Headquarters,

Motro, U
Associate professor, The Hebrew University of Jerusalem,

Meiner, V
Senior geneticist, Hadassah University Hospital,

(Received 21 September 1998; accepted 14 December 1998)

Abstract

Chorionic villus sampling (CVS), prior to pregnancy termination (pre-termination CVS), is suggested as a tool for forensic paternity testing. Unlike the abortion material, which consists of ruptured tissues of fetal and maternal origin, extra-embryonic membranes obtained through CVS can provide an uncontaminated source of fetal tissue for genotyping. We discuss the possibility of confined placental mosaicism (CPM) and its implications on the polymerase chain reaction (PCR) based analyses of short tandem repeats (STRs) and the D1S80 loci.

Keywords:
forensic science, paternity testing, chorionic villus sampling, confined placental mosaicism, DNA typing, polymerase chain reaction6short tandem repeats, D1S80, CSF1PO, TPOX, THO1, F13AO1, FES/FPS, VWA, LPL, F13B

Paper ID: JFS12044J
DOI: 10.1520/JFS12044J
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