Volume 44, Issue 5 (September 1999)

    STR HUMARA Locus Gene and Genotype Frequencies in Han and Bei Populations in China

    (Received 27 August 1998; accepted 5 January 1999)

    CODEN: JFSOAD

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    Abstract

    For the purpose of the population genetics study of the HUMARA locus, the allele, and genotype frequencies were determined in two Chinese population samples (Han-101, Bei-113) using PCR, PAGE, and silver staining. Fourteen alleles were found. The size of amplified fragments were 258 bp-315 bp. The observed heterozygosities were 0.83 in the Han population and 0.73 in the Bei population respectively. The expected heterozygosities were 0.91 in the Han population and 0.97 in the Bei population respectively. Both populations meet Hardy-Weinberg expectation, Han population x2 = 17.7206, df = 11, p > 0.05; Bei population x2 = 7.4268, df = 10, p > 0.05. The discrimination power were 0.95 in females and 0.89 in males in the Han population, 0.94 in females and 0.88 in males in the Bei population. Thus, the allelic frequency data can be used in the personal identification and parentage testing in the forensic science practice. The PCR test established in this study is robust and reproducible.


    Author Information:

    Shen, B
    Professor, School of Forensic Medicine, Kuming Medical College,

    Chen, GD
    Professor, associate professor, associate professor and associate professor, West China University of Medical Sciences, Chengdu,

    Sun, GY
    Professor, associate professor, associate professor and associate professor, West China University of Medical Sciences, Chengdu,

    Zou, LP
    Lecturer, Court of Justice of Yunnan Province,

    Wu, MY
    Professor, associate professor, associate professor and associate professor, West China University of Medical Sciences, Chengdu,

    Li, RH
    Professor, associate professor, associate professor and associate professor, West China University of Medical Sciences, Chengdu,


    Stock #: JFS12037J

    ISSN: 0022-1198

    DOI: 10.1520/JFS12037J

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    Title STR HUMARA Locus Gene and Genotype Frequencies in Han and Bei Populations in China
    Symposium , 0000-00-00
    Committee E30