ISSN: 0022-1198
CODEN: JFSCA
Page Count: 4

Swiss Caucasian Population Data for 13 STR Loci Using AmpFISTR Profiler Plus and Cofiler PCR Amplification Kits
Budowle, B
Program Manager for DNA Research, Forensic Science Research and Training Center, FBI Academy, VA

Gehrig, C
Institut für Rechtsmedizin der Universität Bern,

Hochmeister, M
Institut für Rechtsmedizin der Universität Bern,

Dirnhofer, R
Institut für Rechtsmedizin der Universität Bern,

(Received 24 August 1998; accepted 30 November 1998)

Abstract

Allele and genotype frequencies for the 13 core STR loci (D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, THO1, TPOX, CSF1PO, and D16S539) were determined in a Swiss Caucasian population sample (n = 206) using two commercially available multiplex PCR kits (AmpFISTR Profiler Plus and AmpFISTR Cofiler) and subsequent electrophoresis on an ABI PRISM CE 310 Genetic Analyzer instrument. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the 13 loci. The allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiple STR locus DNA profile in the Swiss population.

Keywords:
forensic science, Switzerland, Caucasian, population genetics, short tandem repeats, Hardy-Weinberg equilibrium, polymerase chain reaction, DNA typing, DS51358, VWA, FGA, D8S1179, D21511, D18S51, D5S818, D13S317, D7S820, THO1, TPOX, CSF1PO, D16S539

Paper ID: JFS12036J
DOI: 10.1520/JFS12036J
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