Journal Published Online: 01 September 1999
Volume 44, Issue 5

Substitution of H O for Formamide in the Sample Preparation Protocol for STR Analysis Using the Capillary Electrophoresis System: The Effects on Precision, Resolution, and Capillary Life

CODEN: JFSCAS

Abstract

Water has been evaluated as a suitable solvent to replace formamide in the preparation of samples for capillary electrophoresis analysis. Critical aspects relevant to forensic analysis were studied to test the validity of the substitution. Correct assignment of allele labels was reproducibly performed on known samples, and size determination was found to be precise. Three hundred injections, regardless the method of preparation, may be run on a single capillary without loss of precision or resolution.

Author Information

Biega, LA
New York State Police Forensic Investigation Center, Albany, NY
Duceman, BW
New York State Police Forensic Investigation Center, Albany, NY
Pages: 3
Price: $25.00
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Stock #: JFS12034J
ISSN: 0022-1198
DOI: 10.1520/JFS12034J