Volume 44, Issue 5 (September 1999)

    Interpreting DNA Mixtures in Structured Populations

    (Received 3 February 1998; accepted 15 December 1998)

    CODEN: JFSOAD

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    Abstract

    DNA profiles from multiple-contributor samples are interpreted by comparing the probabilities of the profiles under alternative propositions. The propositions may specify some known contributors to the sample and may also specify a number of unknown contributors. The probability of the alleles carried by the set of people, known or unknown, depends on the allelic frequencies and also upon any relationships among the people. Membership of the same subpopulation implies a relationship from a shared evolutionary history, and this effect has been incorporated into the probabilities. This acknowledgment of the effects of population structure requires account to be taken of all people in a subpopulation who are typed, whether or not they contributed to the sample.


    Author Information:

    Weir, BS
    North Carolina State University, Raleigh, NC

    Triggs, CM
    University of Auckland, Private Bag 92019, Auckland,

    Curran, JM
    North Carolina State University, Raleigh, NC

    Buckleton, J
    ESR, Auckland,


    Stock #: JFS12028J

    ISSN: 0022-1198

    DOI: 10.1520/JFS12028J

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    Author
    Title Interpreting DNA Mixtures in Structured Populations
    Symposium , 0000-00-00
    Committee E30