Volume 33, Issue 2 (March 1988)

    A Fatality Involving U4Euh, A Cyclic Derivative of Phenylpropanolamine

    (Received 30 March 1987; accepted 1 June 1987)

    Published Online: March

    CODEN: JFSOAD

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    Abstract

    A fatality following ingestion of diazepam and 4,5-dihydro-4-methyl-5-phenyl-2-oxazolamine, a cyclic derivative of phenylpropanolamine known as U4EuH or 4-methyl aminorex, is described. Solid dosage samples of U4EuH were analyzed using gas chromatography, ultraviolet and infrared spectroscopy, nuclear magnetic resonance, and mass spectrometry. Physiological fluids were analyzed quantitatively by gas chromatography and qualitatively by gas chromatography-mass spectrometry. Concentrations of 4,5-dihydro-4-methyl-5-phenyl-2-oxazolamine were: in blood 21.3 mg/L; in urine 12.3 mg/L. Diazepam concentration in blood was 0.8 mg/L.


    Author Information:

    Davis, FT
    Senior chemist, Orlando Crime Laboratory, Orlando, FL

    Brewster, ME
    Associate director of research, Pharmatec, Inc., Alachua, FL


    Stock #: JFS11971J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11971J

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    Title A Fatality Involving U4Euh, A Cyclic Derivative of Phenylpropanolamine
    Symposium , 0000-00-00
    Committee E30