Journal Published Online: 01 October 1986
Volume 31, Issue 4

The Investigation of Alleged Insecticide Toxicity: A Case Involving Chlordane Exposure, Multiple Sclerosis, and Peripheral Neuropathy

CODEN: JFSCAS

Abstract

A man with no previous medical problems had two documented exposures to an insecticide containing the organophosphorous compounds chlordane and heptachlor. Six months to one year later, he began to experience neurological symptoms which progressed until his death. At autopsy, his brain showed classic findings of multiple sclerosis, and he had a severe peripheral neuropathy. Review of the literature indicates that the findings are not compatible with chlordane toxicity. Some of the factors to be used in determining the casual relationship between toxic exposure and disease processes are discussed.

Author Information

Blisard, KS
University of New Mexico, School of Medicine, Albuquerque, NM
Kornfeld, M
University of New Mexico, School of Medicine, Albuquerque, NM
McFeeley, PJ
University of New Mexico, School of Medicine, Albuquerque, NM
Smialek, JE
University of New Mexico, School of Medicine, Albuquerque, NM
Pages: 6
Price: $25.00
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Stock #: JFS11932J
ISSN: 0022-1198
DOI: 10.1520/JFS11932J