The Investigation of Alleged Insecticide Toxicity: A Case Involving Chlordane Exposure, Multiple Sclerosis, and Peripheral Neuropathy

    Volume 31, Issue 4 (October 1986)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 October 1986

    Page Count: 6


    Smialek, JE
    professor, Office of the Medical Investigator, Albuquerque, NM

    Blisard, KS
    Associate investigator, Research Service, Veteran's Administration Medical Center, Albuquerque, NM

    Kornfeld, M
    Professor, University of New Mexico, School of Medicine, Albuquerque, NM

    McFeeley, PJ
    Medical investigator, Office of the Medical Investigator, Albuquerque, NM

    Abstract

    A man with no previous medical problems had two documented exposures to an insecticide containing the organophosphorous compounds chlordane and heptachlor. Six months to one year later, he began to experience neurological symptoms which progressed until his death. At autopsy, his brain showed classic findings of multiple sclerosis, and he had a severe peripheral neuropathy. Review of the literature indicates that the findings are not compatible with chlordane toxicity. Some of the factors to be used in determining the casual relationship between toxic exposure and disease processes are discussed.


    Paper ID: JFS11932J

    DOI: 10.1520/JFS11932J

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    Title The Investigation of Alleged Insecticide Toxicity: A Case Involving Chlordane Exposure, Multiple Sclerosis, and Peripheral Neuropathy
    Symposium , 0000-00-00
    Committee E30