Volume 31, Issue 4 (October 1986)

    The Investigation of Alleged Insecticide Toxicity: A Case Involving Chlordane Exposure, Multiple Sclerosis, and Peripheral Neuropathy

    Published Online: October

    CODEN: JFSOAD

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    Abstract

    A man with no previous medical problems had two documented exposures to an insecticide containing the organophosphorous compounds chlordane and heptachlor. Six months to one year later, he began to experience neurological symptoms which progressed until his death. At autopsy, his brain showed classic findings of multiple sclerosis, and he had a severe peripheral neuropathy. Review of the literature indicates that the findings are not compatible with chlordane toxicity. Some of the factors to be used in determining the casual relationship between toxic exposure and disease processes are discussed.


    Author Information:

    Smialek, JE
    professor, Office of the Medical Investigator, Albuquerque, NM

    Blisard, KS
    Associate investigator, Research Service, Veteran's Administration Medical Center, Albuquerque, NM

    Kornfeld, M
    Professor, University of New Mexico, School of Medicine, Albuquerque, NM

    McFeeley, PJ
    Medical investigator, Office of the Medical Investigator, Albuquerque, NM


    Stock #: JFS11932J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11932J

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    Author
    Title The Investigation of Alleged Insecticide Toxicity: A Case Involving Chlordane Exposure, Multiple Sclerosis, and Peripheral Neuropathy
    Symposium , 0000-00-00
    Committee E30