ISSN: 0022-1198
CODEN: JFSCA
Page Count: 10

Determination of Carbon Monoxide in Blood by Gas Chromatography Using a Thermal Conductivity Detector
Chace, DH
Professional lecturer, graduate student, and associate professor, George Washington University, DC

Goldbaum, LR
Professional lecturer, graduate student, and associate professor, George Washington University, DC

Lappas, NT
Professional lecturer, graduate student, and associate professor, George Washington University, DC

(Received 11 February 1985; accepted 12 June 1985)

Abstract

A method is described for the gas chromatographic quantitation of carbon monoxide by means of thermal conductivity detection. Carbon monoxide is released from blood samples as small as 0.02 mL using a unique extraction chamber. The method was compared to a standard gas chromatographic and spectrophotometric method of carbon monoxide quantitation. It was comparable to the former with all samples evaluated and apparently more reliable than the latter with decomposed samples.

Keywords:
toxicology, carbon monoxide, blood, chromatographic analysis

Paper ID: JFS11867J
DOI: 10.1520/JFS11867J
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