Volume 29, Issue 1 (January 1984)

    Differentiation of Side Chain Positional Isomers of Amphetamine

    (Received 2 February 1983; accepted 11 April 1983)

    CODEN: JFSOAD

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    Abstract

    The eleven side chain positional isomers of amphetamine can be distinguished using a combination of color tests, thin-layer chromatography, and mass spectrometry. The primary amines, 1-phenylpropylamine and β-methylphenethylamine, exhibited chromatographic behavior similar to amphetamine but were readily differentiated using mass spectrometry. The mass spectra of N-methylphenethylamine was very similar to amphetamine, but using color tests and chromatography it was readily differentiated from amphetamine.


    Author Information:

    Agee, DT
    Regional laboratory supervisor, undergraduate intern, and supervisor, Drug Examination Section, Bureau of Forensic Science, Consolidated Laboratories of Virginia, Richmond, VA

    Scott, J
    Regional laboratory supervisor, undergraduate intern, and supervisor, Drug Examination Section, Bureau of Forensic Science, Consolidated Laboratories of Virginia, Richmond, VA

    Thomas, MN
    Assistant professor and undergraduate research assistant, School of Pharmacy Medical College of Virginia/Virginia Commonwealth University, Richmond, VA

    Shark, RE
    Regional laboratory supervisor, undergraduate intern, and supervisor, Drug Examination Section, Bureau of Forensic Science, Consolidated Laboratories of Virginia, Richmond, VA

    Soine, WH
    Assistant professor and undergraduate research assistant, School of Pharmacy Medical College of Virginia/Virginia Commonwealth University, Richmond, VA


    Stock #: JFS11649J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11649J

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    Author
    Title Differentiation of Side Chain Positional Isomers of Amphetamine
    Symposium , 0000-00-00
    Committee E30