Volume 29, Issue 1 (January 1984)

    Tissue Concentrations at Autopsy in Infants and Children Receiving Therapeutic Digoxin

    (Received 12 February 1983; accepted 17 May 1983)

    CODEN: JFSOAD

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    Abstract

    Therapeutic tissue concentrations of digoxin have been reported for relatively small numbers of infants and children. In forensic medicine, knowledge of these concentration ranges is important for confirming or excluding digoxin overdosage in different age groups. In addition to age and weight, other factors such as dosage, duration of treatment, route of administration, sampling site, time of last dose, and death-autopsy interval may influence tissue concentrations. In this paper we report on tissue concentrations in 36 infants and children who received therapeutic digoxin before death.


    Author Information:

    Hastreiter, AR
    Professor and associate professor, Pediatric Cardiology University of Illinois Hospital, Chicago, IL

    van der Horst, RL
    Professor and associate professor, Pediatric Cardiology University of Illinois Hospital, Chicago, IL


    Stock #: JFS11644J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11644J

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    Author
    Title Tissue Concentrations at Autopsy in Infants and Children Receiving Therapeutic Digoxin
    Symposium , 0000-00-00
    Committee E30