ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 October 1983
Page Count: 7

Toxicological Findings in a Death Resulting from the Ingestion of Trimipramine
Guay, DRP
Clinical pharmacist/instructor, St. Boniface General Hospital, Manitoba

Nokes, JM
Toxicologist/biochemist and registered technologist, Department of Laboratory Medicine, St. Boniface General Hospital, Manitoba

Keenan, JR
Toxicologist, Royal Canadian Mounted Police, Crime Laboratory, Manitoba

Meatherall, RC
Toxicologist/biochemist and registered technologist, Department of Laboratory Medicine, St. Boniface General Hospital, Manitoba

(Received 31 January 1983; accepted 15 March 1983)

Abstract

A fatality following ingestion of the tricyclic antidepressant trimipramine is presented. Whole blood concentrations of trimipramine and its metabolite N-desmethyltrimipramine were measured by gas-lqiuid chromatography and found to be 400 and 1130 ng/mL, respectively. These findings are compared to those of previous unpublished trimipramine fatalities and fatalities caused by other tricyclic antidepressants.

Keywords:
toxicology, death, trimipramine, tricyclic antidepressants

Paper ID: JFS11616J
DOI: 10.1520/JFS11616J
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