Volume 28, Issue 4 (October 1983)

    Toxicological Findings in a Death Resulting from the Ingestion of Trimipramine

    (Received 31 January 1983; accepted 15 March 1983)

    Published Online: October

    CODEN: JFSOAD

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    Abstract

    A fatality following ingestion of the tricyclic antidepressant trimipramine is presented. Whole blood concentrations of trimipramine and its metabolite N-desmethyltrimipramine were measured by gas-lqiuid chromatography and found to be 400 and 1130 ng/mL, respectively. These findings are compared to those of previous unpublished trimipramine fatalities and fatalities caused by other tricyclic antidepressants.


    Author Information:

    Guay, DRP
    Clinical pharmacist/instructor, St. Boniface General Hospital, Winnipeg, Manitoba

    Nokes, JM
    Toxicologist/biochemist and registered technologist, Department of Laboratory Medicine, St. Boniface General Hospital, Winnipeg, Manitoba

    Keenan, JR
    Toxicologist, Royal Canadian Mounted Police, Crime Laboratory, Winnipeg, Manitoba

    Meatherall, RC
    Toxicologist/biochemist and registered technologist, Department of Laboratory Medicine, St. Boniface General Hospital, Winnipeg, Manitoba


    Stock #: JFS11616J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11616J

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    Author
    Title Toxicological Findings in a Death Resulting from the Ingestion of Trimipramine
    Symposium , 0000-00-00
    Committee E30