Volume 28, Issue 4 (October 1983)

    Drugs and Driving: A Systematic Analytical Approach

    (Received 5 January 1983; accepted 25 January 1983)

    Published Online: October

    CODEN: JFSOAD

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    Abstract

    To collect useful epidemiological data about drug involvement in highway safety, it is essential that sensitive and specific analytical procedures be used to establish the presence of and to determine the concentrations of drugs and metabolites in samples collected from drivers. This paper describes a comprehensive and systematic screening procedure requiring 6 mL of blood, which has been used for the analysis of samples collected from injured and fatally injured drivers. The procedure uses radioimmunoassay, gas chromatography with selective detectors, and high performance liquid chromatography. Drugs and metabolites presumptively identified are then confirmed primarily using gas chromatography$#x2014;chemical ionization mass spectrometry.


    Author Information:

    Finkle, BS
    Associate toxicologist, associate director, assistant toxicologist, and director, Center for Human Toxicologiy, University of Utah, Salt Lake City, UT

    Crouch, DJ
    Associate toxicologist, associate director, assistant toxicologist, and director, Center for Human Toxicologiy, University of Utah, Salt Lake City, UT

    Chinn, DM
    Associate toxicologist, associate director, assistant toxicologist, and director, Center for Human Toxicologiy, University of Utah, Salt Lake City, UT

    Peat, MA
    Associate toxicologist, associate director, assistant toxicologist, and director, Center for Human Toxicologiy, University of Utah, Salt Lake City, UT


    Stock #: JFS11603J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11603J

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    Author
    Title Drugs and Driving: A Systematic Analytical Approach
    Symposium , 0000-00-00
    Committee E30