The Determination of Cocaine and Its Major Metabolite, Benzoylecgonine, in Postmortem Fluids and Tissues by Computerized Gas Chromatography/Mass Spectrometry

    Volume 28, Issue 4 (October 1983)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 October 1983

    Page Count: 7


    Griesemer, EC
    Supervising criminalist, senior criminalist, and medical examiner, Los Angeles County Medical Examiner-Coroner, Los Angeles, CA

    Raftogianis, L
    Mass spectroscopist, Finnigan Corp., San Jose, CA

    Budd, RD
    Supervising criminalist, senior criminalist, and medical examiner, Los Angeles County Medical Examiner-Coroner, Los Angeles, CA

    Noguchi, TT
    Supervising criminalist, senior criminalist, and medical examiner, Los Angeles County Medical Examiner-Coroner, Los Angeles, CA

    Liu, Y
    Fellow in toxicology, Forensic Sciences Institute, Ministry of Public Security, Beijing,

    (Received 24 January 1983; accepted 28 February 1983)

    Abstract

    An analytical procedure for the simultaneous determination of both cocaine and benzoylecgonine in postmortem fluid and tissue samples has been developed by using computerized gas chromatography/mass spectrometry and gas chromatography using a nitrogen/phosphorus (N/P) detector. Both methods are accurate and sensitive and allow the determination of tissue concentrations of cocaine and benzoylecgonine as low as 0.015 μg/mL.


    Paper ID: JFS11597J

    DOI: 10.1520/JFS11597J

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    Title The Determination of Cocaine and Its Major Metabolite, Benzoylecgonine, in Postmortem Fluids and Tissues by Computerized Gas Chromatography/Mass Spectrometry
    Symposium , 0000-00-00
    Committee E30