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    Volume 28, Issue 4 (October 1983)

    The Determination of Cocaine and Its Major Metabolite, Benzoylecgonine, in Postmortem Fluids and Tissues by Computerized Gas Chromatography/Mass Spectrometry

    (Received 24 January 1983; accepted 28 February 1983)

    Published Online: October

    CODEN: JFSOAD

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    Abstract

    An analytical procedure for the simultaneous determination of both cocaine and benzoylecgonine in postmortem fluid and tissue samples has been developed by using computerized gas chromatography/mass spectrometry and gas chromatography using a nitrogen/phosphorus (N/P) detector. Both methods are accurate and sensitive and allow the determination of tissue concentrations of cocaine and benzoylecgonine as low as 0.015 μg/mL.


    Author Information:

    Griesemer, EC
    Supervising criminalist, senior criminalist, and medical examiner, Los Angeles County Medical Examiner-Coroner, Los Angeles, CA

    Raftogianis, L
    Mass spectroscopist, Finnigan Corp., San Jose, CA

    Budd, RD
    Supervising criminalist, senior criminalist, and medical examiner, Los Angeles County Medical Examiner-Coroner, Los Angeles, CA

    Noguchi, TT
    Supervising criminalist, senior criminalist, and medical examiner, Los Angeles County Medical Examiner-Coroner, Los Angeles, CA

    Liu, Y
    Fellow in toxicology, Forensic Sciences Institute, Ministry of Public Security, Beijing,


    Stock #: JFS11597J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11597J

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    Title The Determination of Cocaine and Its Major Metabolite, Benzoylecgonine, in Postmortem Fluids and Tissues by Computerized Gas Chromatography/Mass Spectrometry
    Symposium , 0000-00-00
    Committee E30