Volume 28, Issue 3 (July 1983)

    A Feasibility Study of Human Leukocyte Antigen (HLA) Typing for Dried Bloodstains

    (Received 4 November 1982; accepted 17 January 1983)

    Published Online: July

    CODEN: JFSOAD

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    Abstract

    This paper constitutes a feasibility report on the use of the human leukocyte antigen (HLA) system for the typing of dried bloodstains. Antigens tested include the HLA-A2, A3, A10, B7, B8, and B14 alleles. An aging study conducted on A3 positive bloodstains showed that HLA-A3 could be reliably detected on bloodstains stored up to 30 days at 22°C Unlike most earlier reports on HLA typing of bloodstains, no cross-reactivity problems were detected with the antisera used in this study. In addition to the successful typing of bloodstains, we were also able to type fresh, neat seminal and saliva stains in the A2 and A10 antigenic systems.


    Author Information:

    Reisner, EG
    Director, HLA Laboratory, Duke University Medical Center, Durham, NC

    Turner, LL
    Forensic serologist and intern, North Carolina State Bureau of Investigation, Raleigh, NC

    Nelson, MS
    Forensic serologist and intern, North Carolina State Bureau of Investigation, Raleigh, NC


    Stock #: JFS11556J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11556J

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    Title A Feasibility Study of Human Leukocyte Antigen (HLA) Typing for Dried Bloodstains
    Symposium , 0000-00-00
    Committee E30