ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 July 1983
Page Count: 7

A Feasibility Study of Human Leukocyte Antigen (HLA) Typing for Dried Bloodstains
Reisner, EG
Director, HLA Laboratory, Duke University Medical Center, NC

Turner, LL
Forensic serologist and intern, North Carolina State Bureau of Investigation, NC

Nelson, MS
Forensic serologist and intern, North Carolina State Bureau of Investigation, NC

(Received 4 November 1982; accepted 17 January 1983)

Abstract

This paper constitutes a feasibility report on the use of the human leukocyte antigen (HLA) system for the typing of dried bloodstains. Antigens tested include the HLA-A2, A3, A10, B7, B8, and B14 alleles. An aging study conducted on A3 positive bloodstains showed that HLA-A3 could be reliably detected on bloodstains stored up to 30 days at 22°C Unlike most earlier reports on HLA typing of bloodstains, no cross-reactivity problems were detected with the antisera used in this study. In addition to the successful typing of bloodstains, we were also able to type fresh, neat seminal and saliva stains in the A2 and A10 antigenic systems.

Keywords:
forensic science, human leukocyte antigen, antigen systems, genetic typing

Paper ID: JFS11556J
DOI: 10.1520/JFS11556J
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