ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 April 1983
Page Count: 6

Detection of Basic Drugs (Methamphetamine, Antidepressants, and Nicotine) from Human Hair
Ishiyama, I
Professor and chairman of department, assistant of department, and research fellow of department, Teikyo University School of Medicine,

Toshida, S
Professor and chairman of department, assistant of department, and research fellow of department, Teikyo University School of Medicine,

Nagai, T
Professor and chairman of department, assistant of department, and research fellow of department, Teikyo University School of Medicine,

(Received 18 June 1982; accepted 30 August 1982)

Abstract

Human hair contains methamphetamine, amitriptyline, imipramine, nicotine, and their metabolites in some amount, which can be detected by routine toxicological methods. Sometimes, the level of drugs reaches over 100 μg/g. Animal experiments indicate that these drugs are found solely in sections of hair grown after administration of the drugs. The negative stage after the administration of drugs means that the hair section containing drugs has not come out of the hair follicle. Toxicological examination of the hairs may give some clue helping to identify the chronology of the intoxication.

Keywords:
toxicology, hair, methamphetamine, tricyclic antidepressants, nicotine, intoxication chronology

Paper ID: JFS11518J
DOI: 10.1520/JFS11518J
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