ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 April 1982
Page Count: 13

Analysis of Fatalities from Acute Narcotism in a Major Urban Area
Pasi, A
From the Office of the Chief Medical Examiner-Coroner, City and County of San Francisco, and the Toxicology Activity, Department of Pharmacology, School of Medicine, University of California at San Francisco. Dr. Pasi is currently at the Gerichtlich-medizinisches Institut, University of Zurich,

Stephens, BG
From the Office of the Chief Medical Examiner-Coroner, City and County of San Francisco, and the Toxicology Activity, Department of Pharmacology, School of Medicine, University of California at San Francisco. Dr. Pasi is currently at the Gerichtlich-medizinisches Institut, University of Zurich,

Hine, CH
From the Office of the Chief Medical Examiner-Coroner, City and County of San Francisco, and the Toxicology Activity, Department of Pharmacology, School of Medicine, University of California at San Francisco. Dr. Pasi is currently at the Gerichtlich-medizinisches Institut, University of Zurich,

Allison, DJ
From the Office of the Chief Medical Examiner-Coroner, City and County of San Francisco, and the Toxicology Activity, Department of Pharmacology, School of Medicine, University of California at San Francisco. Dr. Pasi is currently at the Gerichtlich-medizinisches Institut, University of Zurich,

Wright, JA
From the Office of the Chief Medical Examiner-Coroner, City and County of San Francisco, and the Toxicology Activity, Department of Pharmacology, School of Medicine, University of California at San Francisco. Dr. Pasi is currently at the Gerichtlich-medizinisches Institut, University of Zurich,

(Received 28 May 1981; accepted 23 October 1981)

Abstract

The incidence of acute, fatal narcotism in San Francisco was determined to be 3.2% of all deaths (10 882) subject to medical examiner's inquiry in a five-year period. Heroin was responsible for the greatest number of these cases, usually accompanied by alcohol or other abused drugs. The median concentration of the heroin metabolite, morphine, in the blood in fatal cases was 20 /¼g/dL. Death from propoxyphene, the second most frequently encountered narcotic, was generally determined to be suicidal, while death from heroin was judged to be accidental. The highest rate occurred in black males between the ages of 21 and 30 years. The three most consistent findings were positive identification of the drug in the body (100% of the cases), pulmonary edema (90.4% of the cases), and microscopic liver changes (71.1% of the cases).

Keywords:
pathology and biology, narcotics, death

Paper ID: JFS11491J
DOI: 10.1520/JFS11491J
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