Volume 27, Issue 1 (January 1982)
Hydromorphone Detected in Bile Following Hydrocodone Ingestion
Two similar cases are reported here in which Tussionex® a preparation containing hydrocodone and phenyltoloxamine, caused or contributed to death. Toxicological analyses revealed a high concentration ratio of hydromorphone to hydrocodone in the bile in both cases. It is postulated that the finding of hydromorphone is due to the metabolism of hydrocodone.