ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 July 1981
Page Count: 7

Fatal Methemoglobinemia Resulting from Ingestion of Isobutyl Nitrite, a “Room Odorizer” Widely Used for Recreational Purposes
Dixon, DS
Deputy medical examiner, chief of laboratory service, and deputy chief of laboratory service, Office of the Chief Medical Examiner, D.C.

Santinga, PH
Deputy medical examiner, chief of laboratory service, and deputy chief of laboratory service, Office of the Chief Medical Examiner, D.C.

Reisch, RF
Deputy medical examiner, chief of laboratory service, and deputy chief of laboratory service, Office of the Chief Medical Examiner, D.C.

(Received 31 July 1980; accepted 1 December 1980)

Abstract

The alkyl nitrites, specifically isobutyl nitrite, have taken a prominent place among those substances enjoying widespread recreational use, primarily in discotheques and during sexual activity. Though the usual route of administration by inhalation has not resulted in any toxicologically verified deaths, the chemical may cause fatal toxic methemoglobinemia if ingested. A case with a fatal outcome is presented, and the chemistry and toxicology of the substance are discussed.

Keywords:
toxicology, isobutyl nitrite, death, drug abuse

Paper ID: JFS11404J
DOI: 10.1520/JFS11404J
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