Simultaneous Determination of Carboxyhemoglobin and Methemoglobin in Victims of Carbon Monoxide Poisoning

    Volume 25, Issue 3 (July 1980)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 July 1980

    Page Count: 4


    Aoki, M
    Senior lecturer, forensic chemist, assistant professor, and professor, Nagoya University School of Medicine, Nagoya,

    Oya, M
    Senior lecturer, forensic chemist, assistant professor, and professor, Nagoya University School of Medicine, Nagoya,

    Suzuki, O
    Senior lecturer, Hamamatsu University School of Medicine, Hamamatsu,

    Yada, S
    Senior lecturer, forensic chemist, assistant professor, and professor, Nagoya University School of Medicine, Nagoya,

    Katsumata, Y
    Senior lecturer, forensic chemist, assistant professor, and professor, Nagoya University School of Medicine, Nagoya,

    (Received 30 May 1979; accepted 24 November 1979)

    Abstract

    Concentrations of methemoglobin (Met-Hb) and carboxyhemoglobin (HbCO) were simultaneously determined in blood samples from the victims of city gas poisoning, fires, and exhaust fumes poisoning. All the samples contained high concentrations of HbCO, although the concentrations for victims of city gas poisoning were significantly higher than those for victims of fires or exhaust fumes poisoning. Only negligible amounts of Met-Hb were detected in the samples from cases of city gas poisoning, while 4.9 to 31.6% of Met-Hb were found in all but one (1.8%) of the samples of the other two causes. Heat denaturation was considered to be the main cause of Met-Hb production in cases of fires, and inhalation of oxides of nitrogen in cases of exhaust fumes poisoning.


    Paper ID: JFS11256J

    DOI: 10.1520/JFS11256J

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    Title Simultaneous Determination of Carboxyhemoglobin and Methemoglobin in Victims of Carbon Monoxide Poisoning
    Symposium , 0000-00-00
    Committee E30