Volume 32, Issue 6 (November 1987)

    Concentrations of Mustard Gas [Bis(2-Chloroethyl)Sulfide] in the Tissues of a Victim of a Vesicant Exposure

    (Received 18 December 1986; accepted 16 March 1987)

    Published Online: November

    CODEN: JFSOAD

      Format Pages Price  
    PDF Version 6 $25   ADD TO CART


    Abstract

    An Iranian soldier died at a toxicological intensive care unit at Munich seven days after a vesicant exposure. At the autopsy the typical symptoms of mustard gas intoxication were found. The vesicant was detected qualitatively by gas chromatography-mass spectrometry (GC-MS) in the abdominal fat and quantified in the tissues and in the body fluids by the following method: (1) extraction by dichloromethane, (2) cleanup of the extracts by thin-layer chromatography (TLC) on silica plates, (3) extractive derivatization with gold-chloride, and (4) quantitative determination by electrothermal atomic absorption spectrometry (ET-AAS). The equal extracts, after heating, served for blanks. The following concentrations were found (milligrams of mustard gas/kilograms of tissue wet weight): brain 10.7, cerebrospinal fluid 1.9, liver 2.4, kidney 5.6; spleen 1.5, lung 0.8, muscle 3.9, fat 15.1, skin 8.4, skin with subcutaneous fatty tissue 11.8, liquid from a skin blister: below detection limit, blood 1.1, and urine: below detection limit.


    Author Information:

    Kretschmer, E
    Assistant professor, assistant, assistant professor, and assistant professor, Institut für Rechtsmedizin, München 2,

    Drasch, G
    Assistant professor, assistant, assistant professor, and assistant professor, Institut für Rechtsmedizin, München 2,

    Kauert, G
    Assistant professor, assistant, assistant professor, and assistant professor, Institut für Rechtsmedizin, München 2,

    von Meyer, L
    Assistant professor, assistant, assistant professor, and assistant professor, Institut für Rechtsmedizin, München 2,


    Stock #: JFS11235J

    ISSN: 0022-1198

    DOI: 10.1520/JFS11235J

    ASTM International
    is a member of CrossRef.

    Author
    Title Concentrations of Mustard Gas [Bis(2-Chloroethyl)Sulfide] in the Tissues of a Victim of a Vesicant Exposure
    Symposium , 0000-00-00
    Committee E30