Drugs and Alcohol in Hypothermia and Hyperthermia Related Deaths: A Retrospective Study

    Volume 32, Issue 6 (November 1987)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Published Online: 1 November 1987

    Page Count: 9


    Kortelainen, M-L
    Assistant doctor in forensic medicine, University of Oulu, Oulu 22,

    (Received 5 February 1987; accepted 26 March 1987)

    Abstract

    Hypothermia and hyperthermia related cases recorded for the period 1973 to 1984 were collected from the files of the Department of Forensic Medicine, University of Oulu, and the necropsy protocols including toxicological results were analyzed. The fact that similar alcohol concentrations were found in both types of fatalities points to the poikilothermic effect of alcohol in humans, as found in animal studies. Both types of deaths seem to be associated with the alcohol elimination phase. Antidepressants and neuroleptics were most often found in the hypothermia cases, but benzodiazepines were also quite frequently present. In spite of the diminished use of barbiturates, these still appear in hypothermia fatalities. Certain other drugs that affect thermoregulation were also noted in solitary cases. Extended toxicological analysis was seldom made in the cases of hyperthermia deaths, and no firm conclusions on the poikilothermic effect of psychotropic drugs could be reached, for example. Therapeutic drug concentrations did not alone predispose the subjects to hypothermia, but appeared in connection with alcohol consumption or chronic diseases.


    Paper ID: JFS11228J

    DOI: 10.1520/JFS11228J

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    Title Drugs and Alcohol in Hypothermia and Hyperthermia Related Deaths: A Retrospective Study
    Symposium , 0000-00-00
    Committee E30