Journal Published Online: 01 November 1987
Volume 32, Issue 6

Comparison of Drug Retention Indices Determined on Packed, Wide Bore Capillary and Narrow Bore Capillary Columns

CODEN: JFSCAS

Abstract

The retention indices of 75 drugs and other compounds of toxicological significance have been measured on SE-30 equivalent, chemically bonded, fused silica capillary columns under isothermal conditions. The data have been assessed to determine the validity of using retention indices measured on packed columns for the identification of compounds eluting from narrow bore thin film or wide bore thick film capillary columns. The results indicate that the extensive retention index data bases published for SE-30 packed columns may be used for the preliminary identification of peaks eluting from capillary columns in toxicological screening. The study also indicates that retention index data bases generated on narrow bore capillary columns are applicable to wide bore thick film capillary columns.

Author Information

Japp, M
Central Research Establishment, Home Office Forensic Science Service, Aldermaston, Reading, Berkshire, England
Gill, R
Central Research Establishment, Home Office Forensic Science Service, Aldermaston, Reading, Berkshire, England
David Osselton, M
Central Research Establishment, Home Office Forensic Science Service, Aldermaston, Reading, Berkshire, England
Pages: 13
Price: $25.00
Related
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Details
Stock #: JFS11217J
ISSN: 0022-1198
DOI: 10.1520/JFS11217J