Journal Published Online: 01 September 1987
Volume 32, Issue 5

Massive Metoprolol Ingestion Associated with a Fatality—A Case Report

CODEN: JFSCAS

Abstract

An unusual fatality involving a 26-year-old male who intentionally ingested approximately 10 g of metaoprolol is presented. Autopsy findings revealed foreign material in the gastric content with an acute thrombosis of the left anterior descending coronary artery. Microscopic studies showed evidence of an extremely early infarct. Metoprolol concentrations in the blood, liver, gastric content, and urine are reported by both capillary gas chromatography and ultraviolet spectrophotometric analysis. A review of the literature confirmed that little information has been published concerning intoxication with this drug.

Author Information

David Riker, C
Broward County Medical Examiner's Office, Fort Lauderdale, FL
Wright, RK
Broward County Medical Examiner's Office, Fort Lauderdale, FL
Matusiak, W
Broward County Medical Examiner's Office, Fort Lauderdale, FL
de Tuscan, BE
Broward County Medical Examiner's Office, Fort Lauderdale, FL
Pages: 6
Price: $25.00
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Stock #: JFS11194J
ISSN: 0022-1198
DOI: 10.1520/JFS11194J